pentobarbital will decrease the level or influence of celecoxib by influencing hepatic enzyme CYP2C9/ten metabolism. Minor/Importance Unidentified.
pentobarbital will lower the extent or effect of alfuzosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.
Coadministration of zuranolone with other CNS depressants may possibly enhance impairment of psychomotor functionality or CNS depressant consequences. If unavoidable, look at dose reduction. .
pentobarbital will lessen the level or effect of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Observe Carefully (1)pentobarbital will reduce the level or result of mestranol by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the extent or effect of flurbiprofen by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Not known.
Keep track of Intently (one)pentobarbital will lessen the extent or outcome of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or result of eltrombopag by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Check.
pentobarbital will lessen the extent or result of efavirenz by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance read more Mysterious.
pentobarbital will lower the extent or result of guanfacine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Solid or moderate CYP3A4 inducers noticeably lessen guanfacine plasma concentrations and elimination half-daily life.
With therapeutic doses of TCAs, barbiturates enhance metabolism and reduce blood concentrations of TCAs.
Monitor Closely (1)pentobarbital will lessen the extent or effect of hydrocodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Warning when discontinuing CYP3A4 inducers which can be coadministered with hydrocodone; plasma concentrations of hydrocodone may well increase and can lead to most likely lethal respiratory depressionSerious - Use Alternate (one)hydrocodone, pentobarbital.
pentobarbital will lower the extent or result of eplerenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
pentobarbital will decrease the extent or result of voriconazole by affecting hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Unknown.